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KMID : 1098420070150020128
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Korean Journal of Medicinal Crop Science
2007 Volume.15 No. 2 p.128 ~ p.131
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Inhibitory Effects of Artemsia capillaris Thumb. on and
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Lee Sung-Jin
Kim Chang-Hyun
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Abstract
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This study was carried out to investigate inhibitory effect of extracts from Artemisia capillaris Thumb. on maltase, sucrase, , nonspecific , and postprandial hyperglycemia. Methanol extract and organic solvent (n-hexane, ethyl acetate, butanol, aqueous) fractions from the medicinal herb were determined for the inhibitory activities against maltase, sucrase and . The methanol extract from A. capillaris strongly inhibited maltase (57%) and (72%) at the concentration of 100 . Among the four fractions (n-hexane, ethyl acetate, butanol, aqueous) examined, the butanol fraction from A. capillaris showed potent inhibitory effects on maltase (73%), sucrase (33%), and (75%) at the concentration of 100 . The butanol fraction from Artemisia capillaris also exhibited significant reductions (20%) of blood glucose elevation in mice loaded with maltose. These results suggest that the extract from Artemisia capillaris can be used as a new nutraceutical for inhibition on postprandial hyperglycemia
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KEYWORD
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Artemisia capillaries Thumb., postprandial hyperglycemia, maltase,
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